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Glucosamine and chondroitin sulfate treatment of hand osteoarthritis

John M Erickson1, Terry M Messer

  • 1Raleigh Hand Center, Raleigh, North Carolina 27609, USA. JohnEricksonMD@gmail.com

The Journal of Hand Surgery
|July 30, 2013
PubMed
Abstract

No abstract available in PubMed .

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Glycosaminoglycans

Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...