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[Allergic reactions to local anesthetics]
F Escolano1, L Aliaga, J Alvarez
1Hospital de l'Esperança, Barcelona.
Revista Espanola De Anestesiologia Y Reanimacion
|May 1, 1990
Summary
Real allergic reactions to local anesthetics are rare. Allergy testing, including prick and provocation tests, effectively identifies patients at risk, guiding safe anesthetic choices.
Area of Science:
- Allergy and Immunology
- Pharmacology
Context:
- Adverse reactions to local anesthetics are a clinical concern.
- Distinguishing true allergy from other adverse effects is crucial for patient management.
Purpose:
- To evaluate the diagnostic accuracy of allergy testing for local anesthetic hypersensitivity.
- To identify safe anesthetic options for patients with suspected reactions.
Summary:
- Thirty-five patients with suspected local anesthetic reactions underwent prick, intradermoreaction, and provocation tests using procaine, lidocaine, and mepivacaine.
- All patients tested negative on prick and provocation tests, suggesting true allergies are infrequent.
- One patient reacted to Hostacain intradermoreaction, but testing without parabens was unavailable.
Impact:
- The study methodology aids in differentiating true local anesthetic allergy from other adverse reactions.
- Findings support the low incidence of genuine local anesthetic allergy.
- Provides guidance for selecting safe local anesthetics in clinical practice.