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Cutaneous manifestations of systemic malignancies: part 2
M Yuste Chaves1, P Unamuno Pérez
1Servicio de Dermatología, Hospital Universitario de Salamanca, Salamanca, Spain. manuelayuste@hotmail.com
Actas Dermo-Sifiliograficas
|July 30, 2013
Summary
Skin manifestations can signal systemic malignancies, aiding early cancer diagnosis. This review categorizes diverse skin conditions, from lesions to hair changes, that may indicate underlying cancer.
Area of Science:
- Dermatology
- Oncology
- Internal Medicine
Background:
- The skin serves as a potential indicator for early detection of systemic malignancies.
- Cutaneous manifestations can precede or accompany various internal cancers.
Purpose of the Study:
- To review and categorize skin conditions associated with systemic malignancies.
- To emphasize the diagnostic value of dermatological findings in oncology.
Main Methods:
- Systematic review of literature on skin conditions and systemic cancers.
- Classification of cutaneous findings based on morphological characteristics.
- Analysis of specific dermatological signs, including lesions, xerosis, pruritus, hair and sweat abnormalities, benign tumors, and oral/nail changes.
Main Results:
- Skin conditions are diverse and can manifest as erosive/blistering lesions, inflammatory papules/nodules, xerosis, exfoliative dermatitis, pruritus, abnormal hair patterns, and sweating disorders.
- Benign tumors may indicate hereditary syndromes linked to visceral cancer risk.
- Oral and nail abnormalities can also be associated with systemic malignancies.
Conclusions:
- The skin plays a crucial role in the early diagnosis of systemic malignancies.
- Recognizing specific dermatological signs is vital for oncological assessment.
- A comprehensive evaluation of skin, hair, nails, and oral mucosa can aid in identifying patients with potential underlying cancers.
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