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A completely solvent-free process for the improvement of erythritol compactibility

Yohei Hoashi1, Yuichi Tozuka, Hirofumi Takeuchi

  • 1NIPRO Corporation Pharmaceutical Research Center, Kusatsu, Japan. hoashi-yohei@nipro.co.jp

International Journal of Pharmaceutics
|July 30, 2013
PubMed
Abstract

Keywords:
CPKD-120CPKD-RTCPSDDirect compressionErythritolPorous silicaRDTRapidly disintegrating tabletSolvent-free processTwin-screw kneadercomposite particle of erythritol and porous silica prepared using a spray dryercomposite particle of erythritol and porous silica prepared using a twin-screw kneader at 120°Ccomposite particle of erythritol and porous silica prepared using a twin-screw kneader at room temperaturerapidly disintegrating tablet

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