Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low-molecular-weight peptides from deer antler velvet: Antioxidant potential, biosafety, and synergistic interaction with nanomelanin.

Journal of advanced pharmaceutical technology & research·2026
Same author

Principled XAI analysis of the deep learning-based landslide susceptibility prediction model.

Scientific reports·2026
Same author

Electrochemical-sensor-assisted lab-in-a-cartridge (EC-LIC) for on-site detection of SARS-CoV-2 with a self-contained heating system.

Biosensors & bioelectronics·2026
Same author

Rice paper adsorbent for gold recovery.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Spatiotemporal genomic patterns of <i>Quercus gilva</i>: decoupling historical isolation from contemporary environmental adaptation.

Forestry research·2026
Same author

Effect of excess and restricted inorganic carbon on biokinetics, nitrous oxide emissions, and microbial community in a full-nitrification bioreactor.

Environmental research·2026
Same journal

GLASS-seq: a gel-anchored, ligation-assisted, scalable biosensing platform for low-cost regional spatial transcriptomics.

Biosensors & bioelectronics·2026
Same journal

CRISPR/Cas12a-based dual-modal signal platform using MIL-101(Fe) for colorimetric and electron spin resonance detection of HPV-16 nucleic acid.

Biosensors & bioelectronics·2026
Same journal

Fully automated centrifugal microfluidic system for self-calibrating isothermal nucleic acid quantification.

Biosensors & bioelectronics·2026
Same journal

Synergistic mode-field pre-expansion and geometric compression in hetero-structured microfibers for ultrasensitive glucose sensing.

Biosensors & bioelectronics·2026
Same journal

An amplification-free dual-readout biosensor integrating colorimetry and single-particle counting for ultrasensitive miRNA detection in esophageal cancer.

Biosensors & bioelectronics·2026
Same journal

An all-in-one microfluidic system via data-driven design for on-site genotyping of genetically modified foods.

Biosensors & bioelectronics·2026
See all related articles

Related Experiment Video

Updated: May 9, 2026

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology
08:27

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

Published on: March 24, 2015

A highly sensitive and label free biosensing platform for wireless sensor node system.

Sang-Gyu Kim1, Hee-Jo Lee, Jung-Hyun Lee

  • 1School of Electrical and Electronic Engineering, Yonsei University, Seoul, South Korea.

Biosensors & Bioelectronics
|July 30, 2013
PubMed
Summary
This summary is machine-generated.

We developed a radio-frequency (RF) biosensor using oscillation frequency deviation for sensitive, real-time detection of biomolecular binding. This label-free platform achieves a low detectable limit of ~1 ng/ml.

Keywords:
BiomoleculeBiosensorRadio-frequencySurface acoustic wave filterWireless sensor node

More Related Videos

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Related Experiment Videos

Last Updated: May 9, 2026

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology
08:27

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

Published on: March 24, 2015

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Area of Science:

  • Biosensors
  • Radio-Frequency Engineering
  • Biomolecular Interactions

Background:

  • Label-free biosensing is crucial for real-time monitoring of biomolecular events.
  • Existing methods may lack sensitivity or speed for certain applications.
  • Radio-frequency (RF) technologies offer potential for sensitive, non-invasive detection.

Purpose of the Study:

  • To propose and demonstrate a novel RF biosensor platform.
  • To enhance biosensor sensitivity using a high-Q factor surface acoustic wave (SAW) filter.
  • To validate the platform's performance with known biomolecular binding systems.

Main Methods:

  • Utilized a 2.4 GHz oscillator circuit incorporating a surface acoustic wave (SAW) filter.
  • Immobilized biomolecules onto a resonator to alter its impedance.
  • Measured oscillation frequency deviation caused by biomolecular binding events.
  • Experimentally tested with biotin-streptavidin and DNA hybridization systems.

Main Results:

  • The RF biosensor demonstrated label-free detection of biomolecular binding.
  • Achieved a low detectable limit of approximately 1 ng/ml for streptavidin and complementary DNA (cDNA).
  • Exhibited a fast, real-time response to target biomolecules.
  • High-Q factor SAW filter effectively amplified small frequency changes into large amplitude variations.

Conclusions:

  • The proposed RF biosensor platform is effective for label-free, real-time biomolecular detection.
  • The use of a high-Q SAW filter significantly enhances system sensitivity.
  • The platform shows promise for various applications requiring sensitive and rapid biomolecular analysis.