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Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Diabetic mastopathy.

Chiu-lung Richie Chan1, Ronnie S L Ho, Tony W H Shek

  • 1Department of Surgery, Queen Mary Hospital, Hong Kong, Hong Kong.

The Breast Journal
|July 31, 2013
PubMed
Summary
This summary is machine-generated.

Diabetic mastopathy, a benign breast condition, affects patients with long-standing diabetes mellitus. Early awareness is crucial as it can mimic breast cancer, potentially causing patient anxiety and unnecessary procedures.

Keywords:
diabetic mastopathyepithelioid fibroblastslymphocytic mastitis

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Published on: January 20, 2019

Area of Science:

  • Endocrinology
  • Oncology
  • Pathology

Background:

  • Diabetic mastopathy is a rare, benign breast condition associated with long-standing diabetes mellitus (DM).
  • It can present as a palpable breast mass, often indistinguishable from breast carcinoma on initial evaluation.
  • This condition can lead to significant patient anxiety and potentially unnecessary interventions.

Purpose of the Study:

  • To review the clinicopathologic features of diabetic mastopathy in a series of patients.
  • To highlight the benign nature of this condition and its association with diabetes mellitus.
  • To increase awareness among surgeons regarding this distinct fibroinflammatory breast entity.

Main Methods:

  • Retrospective review of clinicopathologic features of 10 patients diagnosed with diabetic mastopathy.
  • Detailed description of radiologic and pathologic findings for each case.
  • Analysis of patient history, focusing on diabetes type and duration.

Main Results:

  • Ten patients with diabetic mastopathy were analyzed; only three had type 1 diabetes mellitus.
  • All patients had a history of DM exceeding 10 years.
  • Presentations included unilateral, solitary, palpable breast masses ranging from 1.5 to 5 cm; no malignancies were observed during follow-up.

Conclusions:

  • Diabetic mastopathy is a benign fibroinflammatory condition associated with long-standing diabetes mellitus, not exclusive to type 1 DM.
  • It is essential for surgeons to recognize diabetic mastopathy to avoid misdiagnosis and unnecessary procedures.
  • Awareness of this condition can alleviate patient anxiety and prevent invasive interventions.