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Oncocytic meningioma presenting with intratumoral hemorrhage
Yasuo Sasagawa1, Osamu Tachibana, Takaaki Iida
1Department of Neurosurgery, Kanazawa Medical University, 1-1 Daigaku, Uchinada 920-0293, Ishikawa, Japan.
Abstract:
Oncocytic meningiomas have been recently reported as a rare variant of meningiomas. Immunohistochemical analysis shows that neoplastic cells are positive for antimitochondrial antibodies. We report our first patient with oncocytic meningioma, presenting with intratumoral bleeding. A 72-year-old woman suffered from a disturbance of consciousness. A CT scan showed a tumor with intratumoral hemorrhage. An emergency craniotomy was performed and the tumor and hematoma were removed. Examination of the tumor revealed meningothelial cells with oncocytic change. We discuss the clinicopathological considerations of this uncommon variant and review the pertinent literature.
Insights
Oncocytic meningiomas, a rare brain tumor variant, can present with intratumoral bleeding. This case highlights the importance of recognizing this uncommon meningioma subtype in clinical practice.
Area of Science:
- Neuropathology
- Neurosurgery
- Oncology
Background:
- Oncocytic meningiomas are a recently identified, rare variant of meningiomas.
- Immunohistochemical analysis is key, revealing neoplastic cells positive for antimitochondrial antibodies.
Observation:
- A 72-year-old woman presented with a disturbance of consciousness.
- CT imaging revealed a brain tumor with significant intratumoral hemorrhage.
- Emergency craniotomy was performed for tumor and hematoma removal.
Findings:
- Histopathological examination confirmed meningothelial cells with oncocytic changes.
- The tumor exhibited intratumoral bleeding, a critical clinical presentation.
Implications:
- This case underscores the clinicopathological considerations of oncocytic meningiomas.
- Early recognition and surgical management are crucial for this uncommon variant.
- Further research into the characteristics of oncocytic meningiomas is warranted.
