[Autism and attention deficit hyperactivity disorder: pharmacological intervention]
Alberto Fernández-Jaén1, Daniel Martín Fernández-Mayoralas, Ana Laura Fernández-Perrone
1Hospital Quiron, Pozuelo de Alarcon, Espana.
Revista De Neurologia
|July 31, 2013
Summary
Attention deficit hyperactivity disorder (ADHD) symptoms are common in autism spectrum disorder (ASD). ADHD medications like methylphenidate and atomoxetine may help manage these symptoms in ASD patients, though effectiveness can vary.
Area of Science:
- Neurodevelopmental Disorders
- Pediatric Psychiatry
Context:
- Attention deficit hyperactivity disorder (ADHD) symptoms, including inattention and hyperactivity, are not exclusive to ADHD and frequently co-occur in autism spectrum disorders (ASD).
- Over 50% of individuals with ASD exhibit ADHD-related symptoms, highlighting the significant overlap between these conditions.
Purpose:
- To evaluate the efficacy and tolerability of common ADHD pharmacological treatments in patients with comorbid ADHD and ASD.
- To explore factors influencing treatment outcomes in this specific patient population.
Summary:
- Methylphenidate and atomoxetine, standard ADHD medications, show potential benefits in reducing ADHD symptoms in individuals with ASD.
- However, treatment effectiveness may be reduced, and tolerability slightly poorer in patients with ASD compared to those with ADHD alone.
- Factors such as ASD complexity, intellectual disability, and polypharmacy can influence treatment response.
Impact:
- Methylphenidate and atomoxetine offer a viable therapeutic option for improving attention and self-control in patients with co-occurring ADHD and ASD.
- Further controlled research is necessary to validate these findings and optimize treatment strategies for this population.
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