Choroidal thickness in eyes with tilted disk syndrome

Area of Science:

• Ophthalmology
• Retinal Imaging
• Choroidal Anatomy

Background:

• Tilted disk syndrome is a congenital anomaly.
• Posterior staphyloma can be associated with tilted disk syndrome.
• Choroidal thickness variations may impact visual function.

Purpose of the Study:

• To investigate choroidal thickness in eyes with tilted disk syndrome.
• To compare choroidal thickness with and without posterior staphyloma.
• To identify the location of maximal choroidal thinning.

Main Methods:

• Enhanced-depth imaging optical coherence tomography (EDI-OCT) and high-penetration OCT were used.
• Choroidal thickness was measured at multiple points relative to the fovea.
• Indocyanine green angiography (ICGA) was used for comparison.

Main Results:

• Choroid was significantly thinner inferior to the fovea compared to superior.
• Minimal choroidal thickness was observed 1 mm inferior to the fovea, at the staphyloma edge.
• Thinning of medium-to-large choroidal vessels correlated with reduced overall choroidal thickness.

Conclusions:

• Choroidal thinning in tilted disk syndrome occurs near the posterior staphyloma's upper edge.
• The distribution of medium-to-large choroidal vessels is associated with choroidal thickness.
• These findings may have implications for understanding visual field defects in tilted disk syndrome.