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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Psychomotor development in offspring of mothers with post partum depression]
Loreto Podestá L1, Ana María Alarcón, Sergio Muñoz
1Instituto de Pediatría, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile.
Insights
Mothers experiencing postpartum depression (PPD) are twice as likely to have children with psychomotor development issues. This risk is amplified for single mothers or those in unstable relationships, highlighting PPD
Area of Science:
- Pediatrics
- Psychiatry
- Developmental Psychology
Context:
- Postpartum depression (PPD) significantly impacts offspring development.
- Early identification and intervention are crucial for child well-being.
- Primary care settings offer opportunities to assess PPD and child development.
Purpose:
- To investigate the association between postpartum depression (PPD) and psychomotor development in 18-month-old children.
- To quantify the risk of psychomotor alterations in offspring of mothers with PPD.
- To identify factors modifying this risk in a primary care population.
Summary:
- A cross-sectional study of 360 mother-infant dyads found a 29% prevalence of PPD and a 16% prevalence of psychomotor alterations at 18 months.
- Mothers with PPD showed double the odds (OR=2.0, CI=1.07-3.68) of having offspring with psychomotor alterations.
- The association between PPD and psychomotor alterations was stronger in single mothers and those with unstable partners.
Impact:
- Postpartum depression poses a significant risk to children's psychomotor development.
- Findings underscore the importance of screening for PPD in primary care to mitigate developmental risks.
- Targeted support for mothers with PPD, particularly single or those in unstable relationships, is essential.
Background:
Postpartum depression (PPD) has adverse effects on psychomotor development of the offspring.
Aim:
To evaluate the relationship between PPD and psychomotor development in children aged 18 months, consulting in primary care.
Material And Methods:
Cross-sectional study with 360 infants and their mothers. Children had their psychomotor evaluation at l8 months and mothers completed the Edinburgh Postnatal Depression Scale at 4 and 12 weeks postpartum. The prevalence of both PPD and psychomotor alteration was estimated. The association between PPD and psychomotor alteration, including confounding variables, was estimated through logistic multiple regression analysis.
Results:
The prevalence of PPD and psychomotor alteration was 29 and 16%, respectively Mothers with PPD had twice the probability of having an offspring with psychomotor alteration (Odds ratio = 2.0, confidence intervals = 1.07-3.68). This probability was significantly higher among single mothers or those with an unstable partner.
Conclusions:
PPD has a detrimental impact on psychomotor development of children.
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