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Time trade-off: one methodology, different methods.

Arthur E Attema1, Yvette Edelaar-Peeters, Matthijs M Versteegh

  • 1iBMG/iMTA, Erasmus University, PO Box 1738, 3000 DR, Rotterdam, The Netherlands. attema@bmg.eur.nl

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Summary
This summary is machine-generated.

The time trade-off (TTO) task lacks a standard specification, leading to incomparable health state values. This study discusses TTO variations and offers a checklist to improve consistency in health economic evaluations.

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Area of Science:

  • Health Economics
  • Decision Science
  • Public Health

Background:

  • The time trade-off (TTO) task is crucial for valuing health states in health technology assessments.
  • Current TTO task specifications lack scientific consensus, leading to variations in study methodologies.
  • This heterogeneity results in incomparable health state values, hindering their application in policy decisions.

Purpose of the Study:

  • To review and discuss alternative specifications of the time trade-off (TTO) task found in the literature.
  • To identify the methodological, procedural, and analytical elements that define these TTO specifications.
  • To provide a framework for enhancing the comparability of health state values derived from TTO studies.

Main Methods:

  • Literature review of various time trade-off (TTO) task specifications.
  • Identification and categorization of defining elements (methodological, procedural, analytical).
  • Analysis of how these elements influence health state value estimations.

Main Results:

  • Significant variation exists in TTO task specifications across studies.
  • Key elements influencing health state values include methodological, procedural, and analytical choices.
  • The direction of impact (upward or downward) on health state values is indicated for certain elements.

Conclusions:

  • The lack of standardized TTO specifications impedes the comparability of health state values.
  • A proposed checklist for TTO studies aims to guide researchers in making consistent methodological choices.
  • Adoption of such a checklist can enhance the reliability and comparability of health state values for health technology assessments.