Intussusception caused by intestinal metastasis from lung pleomorphic carcinoma

Intussusception is the second most common abdominal emergency in children. On the contrary, it is rare in adults. Most of adult intussusceptions are caused by definable structural lesions, and about half of these lesions are malignant. However, intussusception caused by gastrointestinal metastasis from lung pleomorphic carcinoma is extremely rare, and only a few case reports have been published thus far. We present a rare case of gastrointestinal metastasis from lung pleomorphic carcinoma causing jejuno-jejunal and colon-colonic intussusceptions, and review the previously 3 published cases. Intussusceptions caused by gastrointestinal metastases should always be considered in the differential diagnosis of patients with lung pleomorphic carcinoma presenting with gastrointestinal symptoms. Metastasis-related intussusception is a poor prognostic indicator in patients with pleomorphic carcinoma, regardless of the treatment.