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An Extra-adrenal Pheochromocytoma Presenting as Malignant Hypertension-A Report of two cases

Mahesh Kumar U1, Pankaj Pande, Ss Savita

  • 1Associate Professor, Department of Pathology, Pratima Institute of Medical Sciences , Karimnagar, India .

Journal of Clinical and Diagnostic Research : JCDR
|August 2, 2013
PubMed

Insights

Malignant hypertension, a severe form of high blood pressure, can rarely be caused by paraganglioma, a type of tumor. This report details two unique cases linking this condition to paraganglioma.

Area of Science:

  • Endocrinology
  • Nephrology
  • Oncology

Background:

  • Malignant hypertension is a critical hypertensive complication with severely elevated blood pressure.
  • It is infrequently secondary to paraganglioma, a neuroendocrine tumor.
  • The association between malignant hypertension and catecholamine-secreting paraganglioma is unique.

Purpose of the Study:

  • To report two rare instances of malignant hypertension.
  • To highlight the association with paraganglioma in unusual locations.

Main Methods:

  • Case report presentation.
  • Review of clinical data and diagnostic findings for two patients.

Main Results:

  • Two patients presented with malignant hypertension.
  • Paraganglioma was identified as the underlying cause in both cases.
  • Tumor locations were tonsil and urinary bladder, which are rare sites for paraganglioma.

Conclusions:

  • Malignant hypertension can be a rare manifestation of paraganglioma.
  • Clinicians should consider paraganglioma in the differential diagnosis of malignant hypertension, even with unusual tumor locations.

Keywords:
ParagangliomaTonsilUrinary bladder

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