Osteocytic canalicular networks: morphological implications for altered mechanosensitivity.

Petar Milovanovic1, Elizabeth A Zimmermann, Michael Hahn

  • 1Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf , Lottestraße 59, 22529 Hamburg, Germany.

ACS Nano
|August 6, 2013
PubMed
Summary

Aging significantly reduces the bone canalicular network, impacting osteocyte communication and mechanosensing. This deterioration in bone cell connectivity contributes to increased fragility in elderly individuals.

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