[Preliminary report of efficacy of diabetic polyneuropathy treated with large dose inositol]

Ten diabetics with polyneuropathy were studied by taking 6g inositol tablets (each tablet contains 0.25g inositol) per day for three months. The results showed that large dose inositol could reduce the severity of clinical symptoms, but there was no improvement of the nerve conduction velocity. The possible mechanism of these changes was discussed. According to the clinical observation of the therapeutic effect in those 10 cases, the authors would deem that large dose inositol is an effective drug for diabetic polyneuropathy, and it is worthy of further clinical trial, but other sensitive indicators should be used to evaluate the efficacy of this drug.