Related Experiment Video
Updated: May 9, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
Published on: March 12, 2016
A curious case of glaucoma?
Elizabeth L Pinney1, Henry A Ferreyra1, Larry Frohman2
1Department of Ophthalmology, Shiley Eye Center, University of California, San Diego, La Jolla, California.
Abstract:
An 84-year-old woman diagnosed with primary open-angle glaucoma was referred because her optic nerve appearance did not account for her visual field deficits. Further evaluation showed loss of color vision and rapid progression of visual field defects. Electroretinography revealed abnormal scotopic and photopic responses. Blood samples were positive for anti-retinal antibodies, but a malignancy work-up was negative, consistent with non-paraneoplastic autoimmune retinopathy.
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