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Related Concept Videos

Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
The Thyroid Gland01:23

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
The Parathyroid Glands00:59

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...

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Related Experiment Video

Updated: May 9, 2026

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
05:41

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Hürthle cell thyroid adenoma with an eggshell calcification: sonographic-pathologic correlation.

Sang Kwon Lee1

  • 1Department of Radiology, Dongsan Medical Center, Keimyung University School of Medicine, 56 Dalseong-ro, Jung-gu, Daegu, 700-712, Republic of Korea.

Journal of Clinical Ultrasound : JCU
|August 6, 2013
PubMed
Summary
This summary is machine-generated.

This study highlights a rare Hürthle cell thyroid adenoma case. The thyroid nodule featured distinctive eggshell calcification, important for diagnosis.

Keywords:
Hürthle cell adenomacalcificationneckthyroidultrasonography

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Area of Science:

  • Endocrinology
  • Radiology
  • Pathology

Background:

  • Thyroid nodules are common, requiring accurate diagnostic methods.
  • Hürthle cell adenomas are a specific type of thyroid neoplasm.
  • Eggshell calcification is a rare sonographic finding in thyroid nodules.

Observation:

  • A 58-year-old woman presented with a hypoechoic thyroid mass.
  • Sonography revealed continuous eggshell calcification and intranodular vascularity.
  • Pathology confirmed dystrophic eggshell-type calcification within the adenoma.

Findings:

  • Sonographic and pathological correlation of Hürthle cell thyroid adenoma.
  • Demonstration of eggshell calcification as a key sonographic feature.
  • Identification of calcification location between the capsule and tumor matrix.

Implications:

  • Hürthle cell adenoma should be considered in the differential diagnosis of thyroid nodules with eggshell calcification.
  • This case emphasizes the importance of correlating imaging findings with pathological results.
  • Enhanced understanding of rare sonographic presentations of thyroid neoplasms.