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Updated: May 9, 2026

Primary Sjogren's Syndrome Associated with Lung Adenocarcinoma: Probing the Potential Common Pathogenic Mechanisms and Experimental Verification

Primary Sjogren's Syndrome Associated with Lung Adenocarcinoma: Probing the Potential Common Pathogenic Mechanisms and Experimental Verification

Published on: September 20, 2024

Primary localised laryngeal amyloidosis.

Ferhat Bozkus¹, Turgay Ulas, Ismail Lynen

¹Department of Otolaryngology, Head and Neck Surgery, Harran Unviersity, Sanliurfa,Turkey. drferhat65@hotmail.com

JPMA. the Journal of the Pakistan Medical Association

|August 7, 2013

Summary

Primary localized laryngeal amyloidosis is rare. Surgical treatment of this condition in a 42-year-old woman significantly improved hoarseness and breathing difficulties.

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Last Updated: May 9, 2026

Primary Sjogren's Syndrome Associated with Lung Adenocarcinoma: Probing the Potential Common Pathogenic Mechanisms and Experimental Verification

Primary Sjogren's Syndrome Associated with Lung Adenocarcinoma: Probing the Potential Common Pathogenic Mechanisms and Experimental Verification

Published on: September 20, 2024

Area of Science:

Otorhinolaryngology
Pathology
Medical Case Study

Background:

Laryngeal amyloidosis is an uncommon condition.
Its exact cause and development are not fully understood.
Symptoms often include hoarseness, pain, and breathing difficulties.

Observation:

A 42-year-old woman presented with hoarseness and dyspnea.
Histopathological examination of a biopsy confirmed amyloid deposition in the larynx.
No systemic disease was detected.

Findings:

The patient was diagnosed with primary localized laryngeal amyloidosis.
Surgical intervention using microlaryngoscopy under general anesthesia was performed.
Post-surgery, significant improvement in voice and respiration was observed.

Implications:

This case highlights the successful surgical management of primary localized laryngeal amyloidosis.
Early diagnosis and surgical treatment can lead to substantial recovery of laryngeal function.
Further research into the etiology and pathogenesis of laryngeal amyloidosis is warranted.