Increased red cell distribution width level is associated with absence of coronary collateral vessels in patients

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Published on: June 28, 2019

Mustafa Duran1, Onur Kadir Uysal, Ozgür Günebakmaz

  • 1Department of Cardiology, Kayseri Training and Research Hospital, Kayseri, Turkey. mduran2@gmail.com

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|August 7, 2013
PubMed

Insights

High red cell distribution width (RDW) levels were associated with the absence of coronary collateral vessels (CCV) in patients with acute coronary syndrome (ACS). This finding suggests RDW may indicate poorer collateralization in ACS patients.

Area of Science:

  • Cardiology
  • Hematology
  • Biomarkers

Background:

  • Red cell distribution width (RDW) is linked to cardiovascular outcomes.
  • Coronary collateral vessel (CCV) development is crucial in acute coronary syndrome (ACS).

Purpose of the Study:

  • To investigate the association between serum RDW levels and CCV development in ACS patients.

Main Methods:

  • Prospective, cross-sectional study of 226 ACS patients.
  • Measured serum RDW levels on admission.
  • Assessed CCV using coronary angiography and the Rentrop scoring system.

Main Results:

  • RDW levels were significantly higher in patients with no CCV development (Group 1) compared to those with CCV development (Group 2).
  • RDW showed a predictive value for the absence of collaterals (AUC = 0.573).

Conclusions:

  • Elevated serum RDW levels are associated with the absence of CCV in patients with ACS.
  • RDW may serve as a potential indicator of impaired collateralization in ACS.
Abstract

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