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Updated: May 9, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
Published on: January 7, 2019
[Multiple mitral valve aneurysms, mycotic arterial embolism and aneurysms with infective endocarditis]
Mayumi Shinonaga1, Setsuo Kuraoka, Shoh Tatebe
1Department of Cardiovascular Surgery and Thoracic Surgery, Mito Saiseikai General Hospital, Mito, Japan.
Abstract:
A 30-year-old woman with a more than 6-month history of fever, weight loss, general fatigue and dysesthesia of lower extremities was admitted to our hospital with a diagnosis of infective endocarditis. Blood cultures revealed Staphylococcus oralis. Echocardiography revealed severe mitral and moderate tricuspid regurgitation, as well as massive vegetations and aneurysms on the mitral valve. Computed tomography revealed an abdominal aortic aneurysm, left common and external iliac arterial aneurysms, and occlusion of the left common iliac, the deep femoral arteries and the bilateral tibioperoneal trunk. The ankle brachial pressure indices (ABI) were 0.94 (right) and 0.61 (left). She initially underwent mitral valve replacement and tricuspid annuloplasty. On postoperative day 24, the affected segments of the arteries were replaced with a woven Dacron bifurcated graft after resection of the mycotic abdominal and the iliac arterial aneurysms. We could not obtain a sufficient amount of omental pedicle to wrap the prosthesis. Her postoperative course was uneventful and mycotic arterial embolism and aneurysm did not recur.
Insights
This case study details a patient with Staphylococcus oralis infective endocarditis who developed multiple arterial aneurysms and occlusions. Successful surgical repair of both cardiac and vascular issues prevented recurrence.
Area of Science:
- Cardiology
- Vascular Surgery
- Infectious Diseases
Background:
- Infective endocarditis can lead to widespread embolic events and aneurysms.
- Staphylococcus oralis is a less common but significant pathogen in endocarditis.
Observation:
- A 30-year-old woman presented with prolonged symptoms and was diagnosed with Staphylococcus oralis infective endocarditis.
- She had severe valvular regurgitation, multiple arterial aneurysms (aortic, iliac), and arterial occlusions.
- Ankle-brachial pressure indices indicated significant lower extremity ischemia.
Findings:
- The patient underwent successful mitral valve replacement and tricuspid annuloplasty.
- Mycotic abdominal and iliac arterial aneurysms were resected and replaced with a Dacron graft.
- Postoperative recovery was uneventful, with no recurrence of mycotic arterial embolism or aneurysm.
Implications:
- This case highlights the importance of early diagnosis and comprehensive management of infective endocarditis with embolic complications.
- Aggressive surgical intervention for both cardiac and vascular manifestations is crucial for favorable outcomes.
- Multidisciplinary collaboration between cardiology, infectious diseases, and vascular surgery is essential.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Mitral Stenosis I: Introduction
Endocarditis I: Introduction
Mitral Stenosis III: Medical Management
Endocarditis III: Medical Management
Aneurysm I: Introduction
