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Updated: May 9, 2026

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
A BINOL-based ratiometric fluorescent sensor for Zn2+ and in situ generated ensemble for selective recognition of
Shu-Yan Jiao1, Ling-Ling Peng, Kun Li
1Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China. kli@scu.edu.cn xqyu@scu.edu.cn wangxin@scu.edu.cn.
Abstract:
A novel BINOL-based ratiometric fluorescent sensor (R2) is presented, which can selectively respond to Zn(2+) over Cd(2+) and other metal ions with fluorescence enhancement in aqueous solution. The R2 was successfully applied in the imaging of Zn(2+) in living cells. Additionally, the in situ generated R2-Zn(II) ensemble could further serve as a probe to distinguish histidine from other amino acids via a displacement mode.
