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Updated: May 9, 2026
04:53
A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Lipid emulsions in parenteral nutrition: current applications and future developments
Tianyang Ren1, Lin Cong, Yueqi Wang
1Shenyang Pharmaceutical University, Department of Pharmaceutics Science , Shenyang , China.
Expert Opinion on Drug Delivery
|August 8, 2013
Summary
Parenteral lipid emulsions (LEs) are crucial for nutrition. Alternative LEs with optimized fatty acid (FA) profiles may reduce adverse effects compared to conventional soybean oil-based emulsions.
Area of Science:
- Parenteral Nutrition
- Lipid Emulsions
- Fatty Acid Composition
Background:
- Parenteral lipid emulsions (LEs) are vital for energy, essential fatty acids (FAs), and vitamins in parenteral nutrition (PN).
- Conventional soybean oil (SO)-based LEs may cause adverse effects like oxidative stress and inflammation due to their FA composition.
Purpose of the Study:
- To review the characteristics and clinical benefits of alternative parenteral LEs.
- To discuss their application in critically ill, pediatric, and long-term PN patients.
Main Methods:
- Review of existing literature on alternative LEs.
- Analysis of studies involving medium-chain triglyceride (MCT), olive oil (OO), and fish oil (FO) in LE formulations.
Main Results:
- Alternative LEs offer optimized FA composition.
- These emulsions have demonstrated beneficial clinical effects in specific patient populations.
Conclusions:
- Further high-powered studies are needed to fully understand the biological properties of alternative LEs.
- Development of new therapeutic LEs with tailored FA profiles for specific patient needs is recommended.
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