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Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Published on: May 3, 2018

NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function

Sachin Kotak1, Coralie Busso, Pierre Gönczy

  • 1Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.

The EMBO Journal
|August 8, 2013
PubMed
Summary

Nuclear mitotic apparatus protein (NuMA) phosphorylation controls spindle positioning and elongation during cell division. This phosphorylation balance ensures correct spindle function by regulating cortical dynein levels.

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