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Published on: September 11, 2018
A facile method to prepare molecularly imprinted layer-by-layer nanostructured multilayers using postinfiltration and
Yong Zhou1, Mengjiao Cheng, Xiaoqun Zhu
1State Key Laboratory of Chemical Resource Engineering & Key Laboratory of Carbon Fiber and Functional Polymer, Ministry of Education, Beijing University of Chemical Technology , Beijing 100029, China.
ACS Applied Materials & Interfaces
|August 9, 2013
Summary
Researchers developed a simple method for creating molecularly imprinted nanostructured films using layer-by-layer assembly. This approach avoids complex photocross-linkable polymers, enabling robust devices for molecular recognition.
Area of Science:
- Materials Science
- Nanotechnology
- Polymer Chemistry
Background:
- Surface molecular imprinting in layer-by-layer (SMI-LbL) devices traditionally requires photocross-linkable polymers.
- The synthesis of these polymers can be complex and time-consuming.
- Developing simpler, efficient methods for SMI-LbL devices is crucial for advanced applications.
Purpose of the Study:
- To present a facile strategy for preparing molecularly imprinted layer-by-layer nanostructured films.
- To circumvent the need for pre-synthesized photocross-linkable polymers in SMI-LbL device construction.
- To optimize conditions for high-fidelity molecular recognition in the developed films.
Main Methods:
- Utilized traditional layer-by-layer (LbL) assembly procedures.
- Employed post-infiltration of a bifunctional photosensitive cross-linking agent (4,4'-diazostilbene-2,2'-disulfonic acid disodium salt).
- Performed subsequent photocross-linking to form the imprinted nanostructured films.
Main Results:
- Successfully prepared molecularly imprinted layer-by-layer nanostructured films via a facile strategy.
- Achieved a robust SMI-LbL device exhibiting high fatigue-resistance.
- Optimized preparation conditions demonstrated repeated, high-fidelity unloading and rebinding of target molecules.
Conclusions:
- The combination of templating and cross-linking is key to achieving high fidelity and efficiency in SMI-LbL devices.
- This novel strategy simplifies the construction of SMI-LbL devices, making them more accessible.
- The developed films show significant potential for applications requiring selective molecular recognition.
