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Onecut1 is essential for horizontal cell genesis and retinal integrity.

Fuguo Wu1, Renzhong Li, Yumiko Umino

  • 1Department of Ophthalmology/Ross Eye Institute and Developmental Genomics Group, New York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, Buffalo, New York 14203, USA.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|August 9, 2013
PubMed
Summary

Onecut 1 (Oc1) is crucial for horizontal cell (HC) development in the retina. Loss of Oc1 prevents HC formation, impacting photoreceptor survival and visual function.

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