Related Experiment Video
Updated: May 9, 2026
The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics
Published on: October 5, 2016
Bioactive stilbenes from Vitis vinifera grapevine shoots extracts.
Nassima Chaher1, Kamel Arraki, Elsa Dillinseger
1Université de Bejaia, Faculté des Sciences de la Nature et de la vie, Laboratoire de Biochimie Appliquée, Bejaia, 06000, Algérie.
Grapevine shoots yield new stilbenes, including vitisinol C, which shows significant activity against amyloid-β peptide aggregation, offering potential for Alzheimer
Area of Science:
- Phytochemistry
- Neuroscience
- Biochemistry
Background:
- Viticultural residues are a potential source of bioactive stilbenes like resveratrol.
- Grapevine (Vitis vinifera) shoots were investigated for stilbene content.
Purpose of the Study:
- To isolate and identify stilbenes from Vitis vinifera shoots.
- To evaluate the anti-aggregative activity of these stilbenes against amyloid-β peptide.
Main Methods:
- Isolation and identification of stilbenes using spectroscopic analysis, including nuclear magnetic resonance.
- Biological assays to assess anti-aggregative activity against amyloid-β fibril formation.
Main Results:
- A new resveratrol oligomer, (Z)-cis-miyabenol C, was isolated.
- Two new oligostilbenes, vitisinol C and (E)-cis-miyabenol C, were identified.
- Vitisinol C demonstrated significant activity in inhibiting amyloid-β aggregation.
Conclusions:
- Vitis vinifera grapevine shoots are a promising source of novel bioactive stilbenes.
- Vitisinol C exhibits potential therapeutic properties for amyloid-β related conditions.
More Related Videos
07:13Quantification of Violacein in Chromobacterium violaceum and Its Inhibition by Bioactive Compounds
Published on: August 8, 2025
10:40Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
Published on: December 22, 2017