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Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Van de Graaff Generator01:15

Van de Graaff Generator

Van de Graaff generators (or Van de Graaffs) are devices used to demonstrate high voltage due to static electricity that can also be used for research. Robert Van de Graaff first built one in 1931 (based on original suggestions by Lord Kelvin) for use in nuclear physics research.
Van de Graaff uses both smooth and pointed surfaces, conductors, and insulators to generate large static charges and, hence, large voltages. A substantial excess charge can be deposited on the sphere because it moves...
Ventilatory Modes01:14

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Masking and Demasking Agents01:19

Masking and Demasking Agents

EDTA titrations may necessitate masking and demasking agents to temporarily protect a particular metal ion in a mixture from the EDTA reaction. These agents facilitate the sequential analysis of the metal ions by forming stable complexes with some—but not all—metal ions during certain steps.
There are many masking agents, such as cyanide, fluoride, triethanolamine, thiourea, and 2,3-bis(sulfanyl)propan-1-ol (formerly 2,3-dimercapto-1-propanol), with the masking agent chosen based on the metal...
Excess Pressure Inside a Drop and a Bubble01:13

Excess Pressure Inside a Drop and a Bubble

The shape of a small drop of liquid can be considered spherical, neglecting the effect of gravity. This drop can further be considered as two equal hemispherical drops put together due to surface tension. The forces acting on the spherical drop are due to the pressure of the liquid inside the drop, the pressure due to air outside the drop, and the force due to the surface tension acting on the two hemispherical drops.
Suctioning the Oropharyngeal Airway01:25

Suctioning the Oropharyngeal Airway

In preparing for oropharyngeal airway suctioning, a nurse must gather all necessary equipment, including a suction unit with tubing, a prepackaged suction kit, sterile gloves, water or saline for irrigation, a water-soluble lubricant, and additional personal protective equipment (such as a gown, mask, and goggles) to control infections.
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...

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Related Experiment Video

Updated: May 9, 2026

Magnet Assisted Composite Manufacturing: A Flexible New Technique for Achieving High Consolidation Pressure in Vacuum Bag/Lay-Up Processes
09:41

Magnet Assisted Composite Manufacturing: A Flexible New Technique for Achieving High Consolidation Pressure in Vacuum Bag/Lay-Up Processes

Published on: May 17, 2018

Vacuum assist: angel or demon CON.

Timothy W Willcox1

  • 1Green Lane Cardiothoracic Unit, Auckland City Hospital, Auckland, New Zealand. timw@adhb.govt.nz

The Journal of Extra-Corporeal Technology
|August 13, 2013
PubMed
Summary

Vacuum-assisted venous drainage (VAVD) enhances venous return during cardiopulmonary bypass (CPB) but increases arterial emboli due to air entrainment. Careful consideration of CPB circuit design is needed to mitigate risks associated with VAVD.

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering

Background:

  • Vacuum-assisted venous drainage (VAVD) was introduced to improve venous return during cardiopulmonary bypass (CPB).
  • Initially used for smaller cannulas, VAVD later facilitated CPB circuit size reduction.
  • Its adoption was driven by reduced prime volumes and transfusion rates.

Purpose of the Study:

  • To review the historical use and consequences of VAVD in CPB.
  • To highlight the association between VAVD and increased arterial emboli.
  • To emphasize the need for improved CPB circuit design for air handling.

Main Methods:

  • Literature review of VAVD application in cardiopulmonary bypass.
  • Analysis of clinical reports and in vitro/in vivo studies on VAVD.
  • Examination of CPB circuit design considerations related to VAVD.

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Last Updated: May 9, 2026

Magnet Assisted Composite Manufacturing: A Flexible New Technique for Achieving High Consolidation Pressure in Vacuum Bag/Lay-Up Processes
09:41

Magnet Assisted Composite Manufacturing: A Flexible New Technique for Achieving High Consolidation Pressure in Vacuum Bag/Lay-Up Processes

Published on: May 17, 2018

Reduced-gravity Environment Hardware Demonstrations of a Prototype Miniaturized Flow Cytometer and Companion Microfluidic Mixing Technology
13:59

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08:34

Visualization of High Speed Liquid Jet Impaction on a Moving Surface

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Main Results:

  • VAVD use correlated with reduced hematocrit and transfusion rates.
  • Studies consistently report increased arterial emboli with VAVD, linked to air entrainment.
  • Current understanding of gaseous microemboli impact in CPB remains limited.

Conclusions:

  • VAVD's benefits in CPB are accompanied by significant risks, particularly increased embolic load.
  • CPB component design, especially for air handling, requires further attention.
  • The ethical implications of VAVD innovation in CPB warrant careful evaluation.