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Updated: May 9, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Neonatal drug withdrawal
Jane E Barthell1, Jeanne D Mrozek
1Children's Hospital and Clinics of Minnesota, Minneapolis Campus, USA.
Insights
The number of babies born with drug addiction is rising due to increased prenatal drug exposure. This article outlines neonatal drug withdrawal symptoms and proposes prevention and treatment strategies.
Area of Science:
- Neonatal Abstinence Syndrome (NAS) research
- Maternal-fetal medicine
- Pediatric pharmacology
Background:
- Increasing prevalence of prenatal exposure to both illicit and prescribed substances.
- Growing incidence of neonatal drug withdrawal and addiction in newborns.
- Need for standardized diagnostic and management protocols.
Observation:
- Identification of key clinical signs and symptoms indicative of neonatal drug withdrawal.
- Correlation between maternal substance use during pregnancy and infant outcomes.
- Variability in withdrawal severity based on substance type and duration of exposure.
Findings:
- Detailed description of neonatal drug withdrawal manifestations.
- Discussion of non-pharmacological and pharmacological treatment options.
- Emphasis on a multidisciplinary approach involving neonatologists, nurses, and social workers.
Implications:
- Improved early detection and management of neonatal drug withdrawal.
- Enhanced support for affected infants and their families.
- Potential reduction in long-term health complications associated with NAS.
Abstract:
In recent years, the number of babies exposed to both illegal and prescribed drugs during pregnancy has increased. This has led to an increase in the number of babies born with addiction. This article describes the signs of neonatal drug withdrawal and suggests a comprehensive approach to preventing and treating it.
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