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Related Concept Videos

The ABO Blood Group01:12

The ABO Blood Group

The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
Blood Types02:20

Blood Types

Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.

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Updated: May 9, 2026

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
04:43

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah

Published on: June 24, 2025

Discrepancy in ABO blood grouping.

Mohammad Noman Khan1, Taseer Ahmed Khan, Zulfiqar Ahmed

  • 1Department of Physiology, University of Karachi, Karachi, Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|August 13, 2013
PubMed
Summary
This summary is machine-generated.

Blood typing discrepancies can cause transfusion reactions. Careful analysis revealed a rare variant of blood group B, highlighting the need for meticulous blood group typing and population studies.

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Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
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Published on: September 6, 2017

Area of Science:

  • Transfusion Medicine
  • Immunogenetics
  • Clinical Pathology

Background:

  • Transfusion reactions are often caused by ABO blood group discrepancies.
  • Accurate blood typing is crucial for patient safety in transfusions.

Observation:

  • A blood sample showed conflicting results between forward and reverse blood typing.
  • Analysis using standard American Association of Blood Banking protocols was performed.

Findings:

  • The blood sample was identified as a variant of blood group B, not blood group O.
  • This discrepancy highlights potential challenges in routine blood grouping.

Implications:

  • Emphasizes the need for careful blood typing and investigation of discrepancies.
  • Suggests the necessity of further research into blood group variants within the Pakistani population.
  • Aims to prevent transfusion reactions through improved blood grouping accuracy.