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Updated: May 9, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Atrial septal defect closure
Andres F Vasquez1, John M Lasala
1Division of Cardiology, Washington University School of Medicine, St Louis, MO 63110, USA.
Insights
Atrial septal defects (ASDs) are common congenital heart conditions. Percutaneous closure effectively halts right heart chamber volume overload in patients with ASDs.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Adult Congenital Heart Disease
Background:
- Congenital heart disease (CHD) represents a significant cause of US hospital admissions.
- Atrial septal defects (ASDs) are a prevalent form of CHD, particularly ostium secundum ASDs in adults.
- Right cardiac chamber volume overload is a progressive complication of untreated ASDs.
Purpose of the Study:
- To review the current understanding and management of percutaneous closure for atrial septal defects.
- To highlight the importance of ASD closure in preventing cardiac complications.
- To provide an overview of percutaneous techniques for ASD treatment.
Main Methods:
- Literature review focusing on percutaneous closure of atrial septal defects.
- Analysis of data regarding the prevalence and impact of ASDs.
- Synthesis of information on the efficacy of interventional closure methods.
Main Results:
- Atrial septal defects constitute a substantial portion of adult congenital heart conditions.
- Percutaneous closure is an established method for treating ASDs.
- Timely ASD closure mitigates the adverse effects of right heart volume overload.
Conclusions:
- Percutaneous closure is a key therapeutic strategy for atrial septal defects.
- Effective management of ASDs is crucial for improving long-term cardiac health.
- This review emphasizes the role of minimally invasive techniques in treating congenital heart disease.
Abstract:
Congenital heart disease accounted for 0.3% of US hospital admissions in 2007, with 48% related to atrial septal defects (ASDs). More than one-fourth of adult congenital heart defects are ASDs, 75% of which are ostium secundum ASDs. The progressive impact of volume overload of the right cardiac chambers can be halted by ASD closure. This review focuses on percutaneous ASD closure.
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