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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

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Patent ductus arteriosus.

Mehra Anilkumar1

  • 1Department of Cardiology, LAC-USC Medical Center, Keck School of Medicine, Los Angeles, CA 91011, USA. amehra@usc.edu

Cardiology Clinics
|August 13, 2013
PubMed
Summary
This summary is machine-generated.

Patent ductus arteriosus in adults is typically a minor heart defect. Percutaneous closure is a safe and effective treatment for this condition.

Keywords:
Amplatzer duct occluderCongenital defectsCongenital heart diseasePatent ductus arteriosus (PDA)Percutaneous closure

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Area of Science:

  • Cardiology
  • Adult Congenital Heart Disease

Background:

  • Patent ductus arteriosus (PDA) in adults is often an isolated lesion.
  • Larger shunts typically present earlier in childhood due to symptoms.

Purpose of the Study:

  • To describe the presentation and management of adult patent ductus arteriosus.
  • To highlight the efficacy and safety of percutaneous closure for PDA.

Main Methods:

  • Diagnosis often relies on characteristic murmurs or incidental findings from imaging.
  • Transthoracic echocardiography, CT, and MRI angiography are utilized for detection.
  • Percutaneous closure is the primary interventional approach.

Main Results:

  • The percutaneous approach for PDA closure demonstrates a success rate exceeding 98%.
  • Routine antibiotic prophylaxis for subacute bacterial endocarditis is generally not recommended post-closure.

Conclusions:

  • Patent ductus arteriosus in adults is frequently diagnosed incidentally.
  • Percutaneous closure is a highly safe and effective treatment option for adult PDA.
  • Antibiotic prophylaxis guidelines require specific consideration post-intervention.