Related Experiment Videos
Pyodermas: an analysis of 127 cases
Abstract:
In an analysis of 127 patients with pyodermas, 38 (30%) had primary pyodermas and 89 (70%) had secondary pyodermas. Seventy-one percent (71%) of the primary pyodermas were due to Staphylococcus aureus (S. aureus). Five (5%) of the primary pyodermas were due to multiple organisms. Among the patients with secondary pyodermas, 45% were due to S. aureus, 21% Streptococci, 9% Pseudomonas and 9% Proteus species. Forty-four percent (44%) of the secondary pyodermas were due to multiple organisms. S. aureus is highly sensitive to cephalothin, cloxacillin, erythromycin, methicillin and co-trimoxazole. Streptococci are highly sensitive to cephalothin, erythromycin, ampicillin and penicillin. The gram-negative organisms are sensitive to amikacin, gentamicin, kanamycin and co-trimoxazole. Cloxacillin, or erythromycin (for patients with penicillin allergy) is the antibiotic of choice in patients with primary pyodermas. In patients with infected eczemas, first-generation cephalosporin or cloxacillin is the preferred antibiotic. In patients with infected ulcers, a combination of cloxacillin and gentamicin or a cephalosporin effective against the causative agent is most suitable.
Insights
Staphylococcus aureus is the primary cause of pyodermas. Antibiotic selection for pyodermas depends on whether they are primary or secondary, with specific recommendations for Staphylococcus aureus and other common pathogens.
Area of Science:
- Dermatology
- Infectious Diseases
- Microbiology
Background:
- Pyodermas are common bacterial skin infections.
- Understanding causative organisms and their antibiotic sensitivities is crucial for effective treatment.
Purpose of the Study:
- To analyze the prevalence of primary and secondary pyodermas.
- To identify common bacterial pathogens responsible for pyodermas.
- To determine appropriate antibiotic choices based on identified pathogens and clinical presentation.
Main Methods:
- Retrospective analysis of 127 patients diagnosed with pyodermas.
- Identification of causative organisms and assessment of their antibiotic susceptibility.
- Categorization of pyodermas into primary and secondary types.
Main Results:
- 30% of pyodermas were primary, 70% secondary.
- Staphylococcus aureus was the most frequent cause of primary pyodermas (71%).
- Secondary pyodermas involved Staphylococcus aureus (45%), Streptococci (21%), Pseudomonas (9%), and Proteus (9%), with 44% due to multiple organisms.
Conclusions:
- Antibiotic choice for pyodermas should be guided by the specific pathogen and whether the infection is primary or secondary.
- Staphylococcus aureus and Streptococci show high sensitivity to certain antibiotics like cephalothin and erythromycin.
- Gram-negative organisms are sensitive to amikacin, gentamicin, kanamycin, and co-trimoxazole.