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Published on: September 11, 2020
Group A streptococcal emm type prevalence among symptomatic children in Cape Town and potential vaccine coverage
Mark E Engel1, Babu Muhamed, Andrew C Whitelaw
1From the *Department of Medicine, Groote Schuur Hospital and University of Cape Town; †Department of Clinical Laboratory Sciences, Division of Microbiology, National Health Service and University of Cape Town, Cape Town, South Africa; and ‡University of Tennessee Health Science Center, Memphis, TN.
Abstract:
The molecular epidemiology of group A streptococcal pharyngeal infections in children in the Vanguard Community of Cape Town revealed 26 emm types among 157 isolates from 742 subjects. Coverage of a 30-valent vaccine is predicted to be 95% of pharyngitis cases in this population at high risk of rheumatic fever.
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