Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Drugs and depression.

F A Whitlock, L E Evans

    Drugs
    |January 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Drug-induced depression is a growing concern, affecting nearly 3% of the population. Reviewing and adjusting medications is crucial for managing this condition, especially in predisposed individuals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of population structure on protein-yield improvements in spring wheat (Triticum aestivum L. em Thell).

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
    Same author

    Joan of Arc, creative psychopath: is there another explanation?

    Journal of the Royal Society of Medicine·2010
    Same author

    Glycolysis inhibitors negatively bias blood glucose measurements: potential impact on the reported prevalence of diabetes mellitus.

    Journal of clinical pathology·2007
    Same author

    Fatalities caused by the MDMA-related drug paramethoxyamphetamine (PMA).

    Journal of analytical toxicology·2001
    Same author

    Clinical, bacteriologic, serologic, and pathologic features of infections with atypical Taylorella equigenitalis in mares.

    Journal of the American Veterinary Medical Association·2000
    Same author

    A novel surgical technique for vasectomizing boars.

    Journal of the American Veterinary Medical Association·1997
    Same journal

    Botulinum Toxin Type A for Trigeminal and Postherpetic Neuralgia: An Umbrella Review of Systematic Reviews.

    Drugs·2026
    Same journal

    Biologics and Small Molecule Inhibitors: Novel Therapeutic Strategies for Cutaneous Adverse Drug Reactions.

    Drugs·2026
    Same journal

    Use of Sedative-Hypnotic Drugs and the Risk of Developing Alzheimer's Disease: A Systematic Review, Meta-Analysis and Meta-Regression.

    Drugs·2026
    Same journal

    Relacorilant: First Approval.

    Drugs·2026
    Same journal

    Developmental Progress and Future Potential for Inhaled Biologics in the Treatment of Respiratory Diseases.

    Drugs·2026
    Same journal

    Linerixibat: First Approval.

    Drugs·2026
    See all related articles

    Area of Science:

    • Neuroscience
    • Psychiatry
    • Pharmacology

    Background:

    • Depression is a prevalent condition, with nearly 3% of the population affected.
    • Increased drug use impacting neurotransmitters is a likely contributor to rising depression rates.
    • Neurotransmitter level changes in the central nervous system are implicated in some depressive illnesses.

    Purpose of the Study:

    • To highlight the role of medications in causing or exacerbating depression.
    • To emphasize the importance of reviewing drug therapy in patients presenting with depressive symptoms.
    • To differentiate drug-induced depression from other physiological changes or disease reactions.

    Main Methods:

    • Literature review of drugs implicated in causing depression.
    • Analysis of drug mechanisms affecting central nervous system neurotransmitters.

    Related Experiment Videos

  • Clinical assessment of drug therapy in patients with depression.

    • Main Results:

    • Approximately 200 drugs are claimed to cause depression, but a smaller number frequently precipitate symptoms.
    • Commonly implicated drug classes include antipsychotics, barbiturates, ethanol, oral contraceptives, and antihypertensives.
    • Drug-induced depression can occur during therapeutic use (e.g., reserpine) or withdrawal (e.g., fenfluramine).

    Conclusions:

    • Medication review is essential for patients with depression to identify potential drug-induced causes.
    • Adjusting drug therapy based on assessment can help manage drug-induced depression.
    • Distinguishing drug-induced depression from other conditions is critical for appropriate treatment.