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Six-membered spirocycle triggered probe for visualizing Hg2+ in living cells and bacteria-EPS-mineral aggregates
Zheng Yang1, Likai Hao, Bing Yin
1Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an, Shaanxi 710069, PR China.
Organic Letters
|August 14, 2013
Abstract:
A novel rhodamine based probe with a unique six-membered spirocycle was rationally designed for detection of Hg(2+) with greatly improved selectivity, sensitivity, and photostability. The probe has been shown to be suitable for Hg(2+) imaging in living cells and mapping Hg(2+) distribution in living cell-EPS-mineral aggregates under anoxic conditions.

