Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Congenital nephrotic syndrome].

P Fiala1, I Slugen, J Fukal

  • 1Katedry patológie ILF v Bratislave.

Bratislavske Lekarske Listy
|June 1, 1990
PubMed
Summary

Congenital nephrotic syndrome is rare, with only one case found in 2,500 kidney biopsies. Rebiopsy revealed significant changes, highlighting the importance of accurate kidney biopsy sampling for diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structural interpretation of the <sup>31</sup>P NMR chemical shifts in thiophosphate and phosphate: key effects due to spin-orbit and explicit solvent.

Physical chemistry chemical physics : PCCP·2019
Same author

Investigation of an apodized imaged Hartmann wavefront sensor.

Applied optics·2018
Same author

Experimental discrimination of ion stopping models near the Bragg peak in highly ionized matter.

Nature communications·2017
Same author

Maximum Proton Energy above 85 MeV from the Relativistic Interaction of Laser Pulses with Micrometer Thick CH_{2} Targets.

Physical review letters·2016
Same author

Antibody response to chlamydiae in children with asthma and respiratory illness.

Folia microbiologica·2011
Same author

["Tension" and "pressure" osteons - reality or myth?].

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2010

Area of Science:

  • Nephrology
  • Pediatric Pathology
  • Renal Histopathology

Background:

  • Congenital nephrotic syndrome (CNS) is a rare, severe kidney disorder.
  • Finnish type CNS is characterized by specific histopathological findings.
  • Accurate diagnosis relies on detailed renal histopathology.

Observation:

  • A 20-year study of 2,500 kidney biopsies identified only one case of CNS.
  • Three cases of CNS were found in necroptic material during the same period.
  • Initial kidney biopsy showed minimal glomerular changes.

Findings:

  • Rebiopsy revealed mesangial cell proliferation and focal segmental glomerular sclerosis.
  • Cystically dilated tubules and tubulointerstitial changes were observed.
  • Histopathological findings confirmed congenital nephrotic syndrome of the Finnish type.

Implications:

  • This case underscores the diagnostic challenges in congenital nephrotic syndrome.
  • Rebiopsy findings emphasize the critical role of representative renal biopsy sampling.
  • Accurate tissue collection is vital for diagnosing rare pediatric kidney diseases.

Related Experiment Videos