Related Experiment Video
Updated: May 8, 2026

10:54
Extraction of Histones from Clinical Specimens for Epigenetic Profiling by Mass Spectrometry
Published on: November 21, 2025
Surface enhanced Raman scattering based sensitive detection of histone demethylase activity using a
Yu Wang1, Xianghua Deng, Jinwen Liu
1State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China. haotang@hnu.edu.cn jianhuijiang@hnu.edu.cn.
Abstract:
A novel surface enhanced Raman scattering (SERS) based assay using a formaldehyde-selective reactive probe for sensitive detection of activity of histone demethylases (HDMs) by direct observation of by-product formaldehyde was reported.

