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Updated: May 8, 2026

Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo
Published on: August 4, 2021
Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores
Ping Peng1, Chaoming Wang, Zheng Shi
1Department of Chemistry, University of Central Florida, Orlando, FL 32816, USA.
Abstract:
Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus are useful tools for the study of the biological function of CO.
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