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Updated: May 8, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
06:02

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

Clinical survey on contrast-induced nephropathy after coronary angiography

Feng Wang1, Junhui Li, Baorui Huang

  • 1Department of Nephrology and Rheumatology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University , Shanghai , China and.

Renal Failure
|August 16, 2013
PubMed

Insights

Contrast-induced nephropathy (CIN) affects 10.5% of patients undergoing coronary angiography (CAG). Key risk factors include hypotension, heart failure, anemia, and poor renal function, necessitating careful patient monitoring.

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • Contrast-induced nephropathy (CIN) is a significant complication following contrast media administration.
  • Coronary angiography (CAG) is a common procedure where CIN risk is a concern.

Purpose of the Study:

  • To determine the incidence of CIN in patients undergoing CAG.
  • To identify clinical risk factors associated with CIN development in this patient population.

Main Methods:

  • Retrospective analysis of 487 patient records from Shanghai Sixth People's Hospital (January 2008 - July 2009).
  • Evaluation of CIN incidence based on varying conditions and risk stratification (Mehran risk score).
  • Multifactor regression analysis to identify independent risk factors for CIN.

Main Results:

  • The overall incidence of CIN was 10.5%.
  • CIN incidence increased with higher Mehran risk scores, reaching 18.0% in the high-risk group.
  • Preoperative hypotension, heart failure, anemia, and low estimated glomerular filtration rate (eGFR ≤30 mL/min) were identified as significant risk factors.

Conclusions:

  • CIN following CAG is linked to preoperative hypotension, heart failure, anemia, and impaired renal function.
  • Proactive identification and management of at-risk patients are crucial to mitigate CIN incidence.
Abstract

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