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Correlation between Reynolds number and eccentricity effect in stenosed artery models

Ashkan Javadzadegan1, Yasutomo Shimizu, Masud Behnia

  • 1Mechanical and Mechatronic Engineering, School of Aerospace, The University of Sydney, Sydney, NSW, Australia.

Technology and Health Care : Official Journal of the European Society for Engineering and Medicine
|August 17, 2013
PubMed

Insights

Lesion eccentricity in coronary arteries significantly impacts flow recirculation and shear strain. However, this effect becomes negligible as the Reynolds number (Re) increases.

Area of Science:

  • Cardiovascular physiology
  • Biomedical engineering
  • Fluid dynamics

Background:

  • Flow recirculation and shear strain are physiological processes in coronary arteries linked to disease.
  • Lesion eccentricity, independent of stenosis severity, influences these flow dynamics.

Purpose of the Study:

  • To analyze how lesion eccentricity affects transient flow behavior in a coronary artery model.
  • To investigate the correlation between Reynolds number (Re) and the impact of eccentricity on flow patterns.

Main Methods:

  • Utilized transient particle image velocimetry (PIV) in silicone models.
  • Compared models with eccentric versus concentric 70% diameter stenosis.

Main Results:

  • The eccentric model exhibited larger recirculation zones, higher shear strain rates, and greater axial velocities.
  • Eccentricity's greatest impact was on recirculation zone length, and lowest on shear strain rate.
  • A negative correlation was found between Reynolds number (Re) and eccentricity's effects on velocity, shear strain, and recirculation length.

Conclusions:

  • The influence of lesion eccentricity on coronary artery flow dynamics diminishes as the Reynolds number (Re) rises.
  • Higher Re renders eccentricity's impact on flow behavior negligible.
Abstract

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