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Intestinal giardiasis associated with ophthalmologic changes.

M Pettoello Mantovani1, I Giardino, A Magli

  • 1Department of Pediatrics, University of Naples, Italy.

Journal of Pediatric Gastroenterology and Nutrition
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

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Giardiasis in children can cause ocular alterations like "salt and pepper" degeneration. These eye changes often persist even after successful antiparasitic treatment, indicating potential long-term effects.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Infectious Diseases

Background:

  • Giardiasis is a common intestinal parasite infection in children.
  • Ocular manifestations of giardiasis are rarely reported.
  • The
  • salt and pepper
  • pigmented epithelial degeneration is a specific finding.

Purpose of the Study:

  • To investigate the prevalence and characteristics of ocular alterations in children with symptomatic giardiasis.
  • To assess the impact of antiparasitic treatment on these ocular findings.

Main Methods:

  • An ophthalmologic examination was conducted on 90 children diagnosed with symptomatic giardiasis.
  • Ocular findings were documented, and patients were followed for 1 year after treatment.

Related Experiment Videos

  • Control groups of healthy children and children with gastrointestinal symptoms but no giardiasis were included.
  • Main Results:

    • Ocular alterations were observed in 10 out of 90 children.
    • Eight children presented with
    • salt and pepper
    • pigmented epithelial degeneration.
    • These lesions, along with optic disc decoloration, remained unchanged post-treatment.
    • One case of chorioretinitis resolved with corticosteroid and deflazacort treatment.

    Conclusions:

    • Symptomatic giardiasis can be associated with specific ocular findings, notably
    • salt and pepper
    • pigmented epithelial degeneration.
    • These ocular changes appear to be persistent and may not resolve after standard antiparasitic therapy.
    • Further research is needed to understand the pathophysiology and long-term implications of these ocular manifestations.