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Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...

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Updated: May 8, 2026

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Implementation of thromboprophylaxis guidelines.

A Cregan1, J R Higgins, S O'Shea

  • 1Anu Research Centre, UCC Department of Obstetrics and Gynaecology, Cork University Maternity Hospital, Wilton, Cork. alisoncregan@yahoo.com

Irish Medical Journal
|August 20, 2013
PubMed
Summary
This summary is machine-generated.

Maternal deaths from venous thromboembolism (VTE) are high. While many at-risk women received prophylaxis, incorrect dosing was common, highlighting a need for improved VTE risk assessment and management in obstetrics.

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Last Updated: May 8, 2026

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Area of Science:

  • Obstetrics and Gynecology
  • Maternal Health
  • Thrombosis Research

Background:

  • Venous thromboembolism (VTE) is a significant cause of maternal mortality.
  • Royal College of Obstetricians and Gynaecologists (RCOG) has issued guidelines for VTE risk factors and prophylaxis.
  • Cork University Maternity Hospital (CUMH) aimed to assess VTE risk and guideline adherence.

Purpose of the Study:

  • To determine the pattern of VTE risk among pregnant women at CUMH.
  • To evaluate compliance with the 2004 RCOG VTE prophylaxis guidelines.
  • To identify areas for improvement in VTE prevention strategies.

Main Methods:

  • A cross-sectional study involving the review of 364 women's medical charts.
  • Analysis of VTE risk factors, thromboprophylaxis administration, and dosage accuracy.
  • Assessment of body mass index (BMI) recording practices.

Main Results:

  • 40% of women were identified as being at risk for VTE.
  • 69% of at-risk women received thromboprophylaxis, but only 54% received the correct weight-adjusted dose.
  • Morbidly obese women frequently received incorrect doses, and BMI was not consistently recorded.

Conclusions:

  • There is a need to improve awareness of VTE risks and appropriate dosing in obstetric care.
  • Consistent measurement and recording of BMI at booking visits are crucial for VTE risk assessment.
  • Enhanced adherence to VTE prophylaxis guidelines is necessary to reduce maternal morbidity and mortality.