Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Involution of IgE sensitization to house dust mite allergen molecules by age.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2026

Same author

Allergic Rhinitis in the Elderly. In Collaboration With the ARIA Guidelines.

The journal of allergy and clinical immunology. In practice·2026

Same author

Comparison of Allergic Rhinitis Treatments on Utilities and Quality of Life: A MASK-air Study.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026

Same author

Digital health in allergy care: current practices, evidence, and future prospects.

Frontiers in allergy·2026

Same author

Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines-2024-2025 Revision: Part II-Guidelines on Oral and Ocular Treatments.

Allergy·2026

Same author

Real-world evidence on diagnostic pathways and biopsy optimization for PD-L1 and molecular profiling in advanced non-small cell lung cancer: A four-year cohort analysis.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia·2026

Search research articles

Related Experiment Video

Updated: May 8, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Serum biomarkers in elderly asthma.

João Rufo¹, Luís Taborda-Barata, Olga Lourenço

¹CICS-UBI, Health Sciences Research Centre, University of Beira Interior , Covilhã , Portugal and.

The Journal of Asthma : Official Journal of the Association for the Care of Asthma

|August 20, 2013

Summary

Diagnosing asthma in the elderly is challenging, often leading to misdiagnosis and undertreatment. This review explores serum biomarkers for predicting asthma in older adults, highlighting the need for accurate diagnostic tools.

More Related Videos

Murine Model of Allergen Induced Asthma

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Related Experiment Videos

Last Updated: May 8, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Murine Model of Allergen Induced Asthma

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Area of Science:

Pulmonology
Biomarker Research
Geriatric Medicine

Background:

Asthma diagnosis and treatment are often inadequate in the elderly.
This leads to increased disease severity and complications in this population.
Identifying specific asthma phenotypes in older adults is crucial for effective management.

Purpose of the Study:

To review key serum biomarkers for asthma.
To assess their potential in predicting asthma in the elderly population.
To address the challenges of misdiagnosis and undertreatment in elderly asthma patients.

Main Methods:

A comprehensive literature search was conducted on the PubMed database.
Original articles published between 2000 and January 2013 were reviewed.
Focus was on studies investigating serum biomarkers for asthma.

Main Results:

Thirteen relevant serum biomarkers were identified, including IgE, CRP, IL-6, IL-8, IL-17, TNF-α, and YKL-40.
These biomarkers show potential but lack sufficient specificity for definitive asthma diagnosis.
Neutrophilic asthma, common in older patients, requires distinct diagnostic approaches.

Conclusions:

Accurate diagnosis of asthma in the elderly is critical due to diverse phenotypes like neutrophilic asthma.
Serum biomarkers could aid in diagnosing asthma and differentiating it from other obstructive airways diseases.
Currently, no single serum marker offers sufficient specificity for reliable asthma identification in the elderly.