Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Isotonic and Isometric Muscle Contractions01:22

Isotonic and Isometric Muscle Contractions

Two primary types of muscle contractions are isotonic and isometric, each serving unique functions and involving distinct mechanisms. Both isotonic and isometric contractions are integral to the body's complex system of movement and stability. Isotonic exercises contribute significantly to functional strength and movement, while isometric contractions are crucial for maintaining posture and joint stability.
Isotonic contractions
Isotonic contractions occur when a muscle changes length while the...
Motor Unit Stimulation01:20

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open.
Smooth Muscle Contraction01:25

Smooth Muscle Contraction

Smooth muscle contraction is a complex process vital for various bodily functions, from maintaining blood vessel tension to facilitating the movement of food through the digestive tract. Unlike striated muscles, smooth muscle contraction begins more slowly and lasts longer.
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nature of perceived effort and fatigue.

Journal of motor behavior·2013
Same author

Ventilation rates and health: multidisciplinary review of the scientific literature.

Indoor air·2011
Same author

A quantitative structure-activity relationship (QSAR) for a draize eye irritation database.

Toxicology in vitro : an international journal published in association with BIBRA·2010
Same author

Draize Eye Scores and Eye Irritation Thresholds in Man Combined into one Quantitative Structure-Activity Relationship.

Toxicology in vitro : an international journal published in association with BIBRA·2010
Same author

Olfactory detection of ozone and D-limonene: reactants in indoor spaces.

Indoor air·2007
Same author

Cutoff in detection of eye irritation from vapors of homologous carboxylic acids and aliphatic aldehydes.

Neuroscience·2007
Same journal

Expertise Modulates Anticipatory Synergy Adjustments in a Rapid Motor Skill Under Temporal Constraints.

Journal of motor behavior·2026
Same journal

A Boundary of Ideomotor Control: Semantic Labels Bias Selection but Do Not Tune Motor Execution.

Journal of motor behavior·2026
Same journal

Strategies When Choosing Between Movement Options in a Sequential Task.

Journal of motor behavior·2026
Same journal

Transcranial Direct Current Stimulation Combined with Neurofunctional Motor Training in Autistic Children: A Randomized, Sham-Controlled, Double-Blind Clinical Trial.

Journal of motor behavior·2026
Same journal

Individualized Virtual Angle Offset Training for Patients with Stroke.

Journal of motor behavior·2026
Same journal

The Role of Exploratory Procedures in Perceiving Affordances in a Bimanual Wielding Task.

Journal of motor behavior·2026
See all related articles

Related Experiment Video

Updated: May 8, 2026

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies
14:10

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies

Published on: January 31, 2013

Constant effort during static and dynamic muscular exercise.

K B Pandolf1, W S Cain

  • 1a John B. Pierce Foundation Laboratory and Yale School of Medicine.

Journal of Motor Behavior
|August 20, 2013
PubMed
Summary
This summary is machine-generated.

Subjects maintained a constant sense of effort during static handgrip and dynamic cycling exercises. Effort levels declined sharply initially, then stabilized, reflecting differences between static and dynamic tasks.

More Related Videos

Myo-mechanical Analysis of Isolated Skeletal Muscle
08:42

Myo-mechanical Analysis of Isolated Skeletal Muscle

Published on: February 22, 2011

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
14:02

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

Related Experiment Videos

Last Updated: May 8, 2026

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies
14:10

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies

Published on: January 31, 2013

Myo-mechanical Analysis of Isolated Skeletal Muscle
08:42

Myo-mechanical Analysis of Isolated Skeletal Muscle

Published on: February 22, 2011

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
14:02

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

Area of Science:

  • Exercise Physiology
  • Human Performance
  • Sensation and Perception

Background:

  • Understanding how individuals perceive and maintain effort during physical exertion is crucial for exercise science.
  • Previous research has explored effort perception, but direct comparisons between static and dynamic tasks under constant-effort conditions are less common.

Purpose of the Study:

  • To investigate the time course of perceived effort during sustained static handgrip contractions and dynamic cycling.
  • To compare the 'constant-effort' functions between static and dynamic exercise modalities.

Main Methods:

  • Participants performed static handgrip contractions (3 min) at varying percentages of maximum voluntary contraction (MVC).
  • Participants performed dynamic cycling exercise (12 min) at power outputs eliciting 30-85% of maximum oxygen uptake (VO2max).
  • Time-course data for force (handgrip) and power output (cycling) were analyzed.

Main Results:

  • For both tasks, perceived effort functions declined sharply initially, followed by a slower decline towards a steady state.
  • Handgrip force stabilized near 15% MVC, while cycling power output stabilized at levels eliciting <= 50% VO2max.
  • The rate of decline and asymptote differed between static and dynamic tasks, indicating distinct physiological responses.

Conclusions:

  • The perception of effort is not truly constant over time during sustained submaximal static or dynamic exercise.
  • The observed 'constant-effort' decline reflects fundamental differences in the physiological control and metabolic demands of static versus dynamic tasks.
  • These findings contribute to a better understanding of effort regulation during different exercise types.