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Related Concept Videos

Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the generated carbocation,...
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Radical Chain-Growth Polymerization: Chain Branching01:17

Radical Chain-Growth Polymerization: Chain Branching

The skeletal structure of polymers synthesized via radical polymerization is always branched. For example, the polymerization of ethylene by radical polymerization results in a low-density grade of polyethylene with a heavily branched skeletal structure. Here, the radical site abstracts hydrogen from the growing chain, and the radical site shifts from the end (a primary carbon center) to anywhere within the growing chain (a secondary carbon center). Consequently, the part of the chain from the...
Dehydration Synthesis01:15

Dehydration Synthesis

Overview
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
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Anionic Chain-Growth Polymerization: Mechanism01:04

Anionic Chain-Growth Polymerization: Mechanism

The mechanism for anionic chain-growth polymerization involves initiation, propagation, and termination steps. In the initiation step, a nucleophilic anion, such as butyl lithium, initiates the polymerization process by attacking the π bond of the vinylic monomer. As a result, a carbanion, stabilized by the electron‐withdrawing group, is generated. The resulting carbanion acts as a Michael donor in the propagation step and attacks the second vinylic monomer, which acts as a Michael acceptor.

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Updated: May 8, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Single-chain polymer self-assembly using complementary hydrogen bonding units.

Joy Romulus1, Marcus Weck

  • 1Department of Chemistry and Molecular Design Institute, New York University, New York, NY, 10003, USA.

Macromolecular Rapid Communications
|August 20, 2013
PubMed
Summary
This summary is machine-generated.

Researchers synthesized triblock copolymers using ureidoguanosine-diaminonaphthyridine (UG-DAN) for hydrogen bonding. These polymers self-assemble through these specific bonds, even at low concentrations, demonstrating controlled fabrication and intramolecular interactions.

Keywords:
ROMPhydrogen bondingintramolecular foldingself-assembly

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Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

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Area of Science:

  • Polymer Chemistry
  • Supramolecular Chemistry
  • Materials Science

Background:

  • Hydrogen bonding motifs are crucial for self-assembly in supramolecular chemistry.
  • Designing functional polymers with specific recognition pairs enables controlled material properties.

Purpose of the Study:

  • To synthesize novel triblock copolymers incorporating the ureidoguanosine-diaminonaphthyridine (UG-DAN) hydrogen bonding recognition pair.
  • To investigate the controlled polymerization and self-assembly behavior of these functionalized copolymers.

Main Methods:

  • Ring-opening metathesis polymerization (ROMP) was employed for copolymer synthesis.
  • Dynamic light scattering and 1H NMR spectroscopy were used to characterize self-assembly.
  • A modified ureidoguanosine (UG) molecule served as a protecting group for controlled polymerization.

Main Results:

  • Successfully synthesized triblock copolymers with pendant UG-DAN functional groups.
  • Demonstrated controlled polymerization of the norbornene-based DAN monomer using a UG protecting group.
  • Observed self-assembly of the copolymers via complementary hydrogen bonding, even at low dilutions.
  • Indicated the prevalence of intramolecular interactions driving self-assembly.

Conclusions:

  • The developed ROMP strategy allows for the controlled fabrication of functionalized triblock copolymers.
  • The UG-DAN recognition pair effectively drives polymer self-assembly through specific hydrogen bonding.
  • The findings highlight the potential for designing sophisticated supramolecular materials with predictable assembly behavior.