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Updated: May 8, 2026
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Lipid Bilayer Vesicle Generation Using Microfluidic Jetting
Published on: February 21, 2014
Microfluidic jet injection for delivering macromolecules into cells
1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Journal of Micromechanics and Microengineering : Structures, Devices, and Systems
|August 20, 2013
Abstract:
We present a microfluidic based injection system designed to achieve intracellular delivery of macromolecules by directing a picoliter-jet of a solution towards individual cells. After discussing the concept, we present design specification and criteria, elucidate performance and discuss results. The method has the potential to be quantitative and high throughput, overcoming limitations of current intracellular delivery protocols.
