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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Allergic diseases and air pollution.

Suh-Young Lee1, Yoon-Seok Chang, Sang-Heon Cho

  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea.

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Air pollution is a growing global health concern, linked to rising allergic diseases like asthma and eczema. This review explores how pollutants impact allergies and respiratory health, including epigenetic effects.

Keywords:
Air pollutionAllergyEnvironmental exposureTobacco smoke pollution

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Area of Science:

  • Environmental Health
  • Allergology
  • Toxicology

Background:

  • Allergic diseases are increasing globally, particularly in developing nations.
  • Urbanization and energy use have led to higher exposure to diverse air pollutants.
  • Air pollution is a significant environmental risk factor for adverse health outcomes.

Purpose of the Study:

  • To review the detrimental effects of air pollutants on allergic diseases.
  • To examine the role of air pollution in the development and exacerbation of asthma, allergic rhinitis, and eczema.
  • To discuss the impact of air pollutants on epigenetic regulation related to allergies.

Main Methods:

  • Literature review of studies on air pollution and allergic diseases.
  • Analysis of research on specific pollutants like particulate matter, ozone, and nitrogen dioxide.
  • Examination of evidence linking transportation-related pollutants to allergy development.

Main Results:

  • Air pollutants are potent triggers for asthma exacerbation.
  • Emerging evidence links transportation pollutants to allergy development.
  • Exposure to pollutants increases susceptibility to respiratory infections.

Conclusions:

  • Air pollution significantly contributes to the rising prevalence and severity of allergic diseases.
  • Understanding the mechanisms, including epigenetic changes, is crucial for mitigation strategies.
  • Reducing air pollution is essential for public health, especially concerning allergic conditions.