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A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition
Published on: July 21, 2023
First heart transplantation in a small child in Romania
1Department of Cardiovascular Surgery for Children and Adults, University of Medicine and Pharmacy, Mures, Romania. horisuciu@gmail.com
Chirurgia (Bucharest, Romania : 1990)
|August 21, 2013
Summary
Romania
Area of Science:
- Pediatric Cardiovascular Surgery
- Pediatric Cardiology
- Transplantation Medicine
Background:
- Irreducible heart failure in children necessitates advanced interventions.
- Pediatric heart transplantation is a critical treatment option.
- Romania has limited experience in pediatric heart transplantation.
Observation:
- A 3-year-old girl with idiopathic dilated cardiomyopathy and NYHA Class IV heart failure underwent heart transplantation.
- The procedure utilized an orthotopic bicaval technique.
- The patient received triple immunosuppression and prophylactic therapies.
Findings:
- Postoperative recovery was favorable with no signs of rejection at 1 month.
- The child remained in good health 31 months post-transplant.
- Successful pediatric heart transplantation is achievable with experienced teams.
Implications:
- This case marks a significant milestone in Romanian pediatric cardiac surgery.
- Pediatric heart transplantation can be performed with low mortality and morbidity.
- Successful outcomes depend on specialized pediatric cardiovascular surgery and transplantation expertise.
