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Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator

Fabian V Filipp1

  • 1Systems Biology and Cancer Metabolism, Program for Quantitative and Systems Biology, University of California Merced, 5200 North Lake Road, Merced, CA 95343, USA.

Journal of Carcinogenesis
|August 21, 2013
PubMed

Keywords:
6-bisphosphatase6-bisphosphateCancer metabolismMYCNMRPKM1PKM2Warburgcatenincontrolepidermal growth factor receptorfeed-forwardfeedbackfructose-1glutamic-oxalacetic transaminaseglutaminasehypoxia-inducible factor 1-alphaisoformmetabolomicsomicspyruvate dehydrogenasepyruvate dehydrogenase kinasepyruvate kinasepyruvate kinase M2serineserine/arginine-rich splicing factor 3seven in absentia homolog 2signal transducer and activator of transcription 3succinylaminoimidazolecarboxamide ribose-5-phosphatesystems biology

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