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Updated: May 8, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

Flexible access to conformationally-locked bicyclic morpholines.

Rachael Bogacki1, Duncan M Gill, William J Kerr

  • 1Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, Scotland, UK. w.kerr@strath.ac.uk.

Chemical Communications (Cambridge, England)
|August 22, 2013
PubMed
Summary

A new method creates conformationally-locked bicyclic morpholines. This approach allows for diverse, lead-like scaffolds from simple starting materials, aiding drug discovery.

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